Butyrolactone I, ATP-competitive cyclin-dependent kinase (CDK) inhibitor (CAS 87414-49-1) (ab141520) (2024)

Overview

• Product name

  Butyrolactone I, ATP-competitive cyclin-dependent kinase (CDK) inhibitor

• Description

  Cell permeable, selective, ATP-competitive cyclin-dependent kinase (CDK) inhibitor

• Purity

  > 97%

• CAS Number

  87414-49-1

• Chemical structure

  

Properties

• Chemical name

  Methyl (2S)-4-hydroxy-2-[[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]methyl]-3-(4-hydroxyphenyl)-5-oxofuran-2-carboxylate

• Molecular weight

  424.50

• Molecular formula

  C₂₄H₂₄O₇

• PubChem identifier

  51340302

• Storage instructions

  Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

• Solubility overview

  Soluble in DMSO to 10 mM and in ethanol to 50 mM

• Handling

  Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  Refer to SDS for further information.

  Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

• SMILES

  CC(=CCC1=C(C=CC(=C1)CC2(C(=C(C(=O)O2)O)C3=CC=C(C=C3)O)C(=O)OC)O)C

• Source

  Synthetic

• Research areas

  • Cell Biology
  • Cell Cycle
  • Cyclins

  • Cell Biology
  • Cell Cycle
  • Kinases/Phosphatases
  • Cdks

  • Neuroscience
  • Neurology process
  • Neural Signal Transduction

  • Cell Biology
  • Cell Cycle
  • Cyclins
  • Cyclin B Family

  • Cell Biology
  • Cell Cycle
  • Cyclins
  • Cyclin E Family

  • Neuroscience
  • Neurology process
  • Neurodegenerative disease
  • Other

  • Epigenetics and Nuclear Signaling
  • Cell cycle
  • Cyclins
  • Cyclin B Family

  • Epigenetics and Nuclear Signaling
  • Cell cycle
  • Cyclins
  • Cyclin E Family

  • Epigenetics and Nuclear Signaling
  • Cell cycle
  • Kinases/Phosphatases
  • Cdks

  • Cancer
  • Cell cycle
  • Cyclins
  • Cyclin B family

  • Cancer
  • Cell cycle
  • Cyclins
  • Cyclin E family

  • Cancer
  • Cell cycle
  • Kinases/phosphatases
  • Cdks

  • Biochemicals
  • Chemical Type
  • Biochemicals

  • Biochemicals
  • Pharmacology
  • Enzymes
  • Kinase
  • Cyclin-dependent kinase
  • Inhibitors

  • Biochemicals
  • Pharmacology
  • Signaling
  • Cyclin-dependent kinase
  • Inhibitors

  • Biochemicals
  • Research Area
  • Cancer
  • Cyclin-dependent kinase
  • Inhibitors

• Chemical Structure - Butyrolactone I, ATP-competitive cyclin-dependent kinase (CDK) inhibitor (ab141520)

  2D chemical structure image of ab141520, Butyrolactone I, ATP-competitive cyclin-dependent kinase (CDK) inhibitor

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

• SDS download

  Country/Region

  Language

  

• Datasheet download

  Download

ab141520 has been referenced in 1 publication.

• Harasimov K et al. Actin-driven chromosome clustering facilitates fast and complete chromosome capture in mammalian oocytes. Nat Cell Biol 25:439-452 (2023). PubMed: 36732633